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Avient’s Oxygen-scavenging Additive Masterbatch Limits Degradation of Drugs

Published on 2020-09-18. Edited By : SpecialChem

TAGS:  Additives for Packaging    

Avient’s Oxygen-Scavenging Additive Masterbatch Limits Degradation of Drugs Avient Corporation featured its MEVOPUR™ ProTect oxygen-scavenging additive masterbatch at Medtec China 2020. The recent addition to the proven MEVOPUR™ medical and pharmaceutical portfolio limits oxygen (O2) degradation for drugs and nutraceuticals stored in PET bottles, even in transparent mono-layer versions.

Meeting Longer Shelf-life Requirement in Packaging


MEVOPUR™ ProTect delivers active molecules with excellent scavenging performance for O2 permeating through container walls. With this performance, it is possible to maintain significantly lower levels of O2 over extended periods in mono-layer bottles and refrigerated environments.

Even with low concentrations of the active ingredient compared to alternative products, MEVOPUR™ ProTect helps packaging to meet the two-year (or longer) shelf-life often required in pharmaceutical packaging. In addition, tests have shown that PET pre-forms made with this masterbatch do not need special storage conditions to maintain oxygen scavenging capabilities after 3 months.

Similar to food and beverage applications, PET use for pharma packaging is on the rise. Unlike food and beverages, however, pharmaceuticals often need shelf lives spanning two or more years. HDPE, a former material of choice for these applications, is being replaced by PET, which offers transparency in addition to long-term shelf life,” said Steve Duckworth, global head of marketing and business development, Healthcare, CAI, at Avient.

Masterbatch Maintain Oxygen Levels Below 1 ppm


Oxygen scavenging performance depends on a number of factors including packaging design, additive loading, and target oxygen levels over time. However, in one test, a 500 ml, 400 micron monolayer PET bottle with 3.6 percent loading of MEVOPUR™ ProTect masterbatch was able to maintain oxygen levels below 1 ppm for more than 590 days, compared to just 22 days for untreated PET, and 63 days for a competitive oxygen scavenger.

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Source: Avient
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